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MERCK MANUAL
Veterinary Manual
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Veterinary
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Pharmacology
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Antibacterial Agents
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Antibacterial Agents
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Beta-Lactam Antimicrobial Use in Animals
Antimicrobial Activity
Mode of Action
Bacterial Resistance
Use of Penicillins in Animals
Classes by Spectrum
Narrow-spectrum Beta-Lactamase–sensitive Penicillins
Broad-spectrum Beta-Lactamase–sensitive Penicillins
Broad-spectrum Beta-Lactamase–sensitive Penicillins With Extended Spectra
Beta-Lactamase–protected Penicillins
Narrow-spectrum Beta-Lactamase–resistant Penicillins
Carbapenems
General Properties
Structure-activity Relationships
Pharmacokinetic Features
Absorption
Distribution
Biotransformation
Excretion
Pharmacokinetic Values
Therapeutic Indications and Dose Rates
Special Clinical Concerns
Adverse Effects and Toxicity
Interactions
Effects on Laboratory Tests
Drug Withdrawal and Milk Discard Times
Cephalosporins and Cephamycins Use in Animals
Classes and Antibacterial Spectra
First-generation Cephalosporins
Second-generation Cephalosporins
Third- and Fourth-generation Cephalosporins
General Properties
Antimicrobial Activity
Bacterial Resistance
Pharmacokinetic Features
Absorption
Distribution
Biotransformation
Excretion
Pharmacokinetic Parameters
Therapeutic Indications and Dose Rates
Special Clinical Concerns
Adverse Effects and Toxicity
Interactions
Effects on Laboratory Tests
Drug Withdrawal and Milk Discard Times
Aminoglycosides Use in Animals
Classes
Narrow-spectrum Aminoglycosides
Expanded-spectrum Aminoglycosides
Miscellaneous Aminoglycoside Antimicrobials
General Properties
Antimicrobial Activity
Mode of Action
Bacterial Resistance
Antibacterial Spectra
Pharmacokinetic Features
Absorption
Distribution
Biotransformation, Excretion, and Pharmacokinetic Values
Therapeutic Indications and Dose Rates
Special Clinical Concerns
Adverse Effects and Toxicity
Interactions
Effects on Laboratory Tests
Drug Withdrawal and Milk Discard Times
Miscellaneous Aminocyclitol Antimicrobials
Quinolones, Including Fluoroquinolones, Use in Animals
Classes
General Properties
Antimicrobial Activity
Mode of Action
Bacterial Resistance
Antimicrobial Spectra
Pharmacokinetic Features
Absorption
Distribution
Biotransformation
Excretion
Pharmacokinetic Values
Therapeutic Indications and Dose Rates
Special Clinical Concerns
Adverse Effects and Toxicity
Interactions
Effects on Laboratory Tests
Drug Withdrawal and Milk Discard Times
For More Information
Sulfonamides and Sulfonamide Combinations Use in Animals
Classes
Standard-Use Sulfonamides
Highly Soluble Sulfonamides Used for Urinary Tract Infections
Potentiated Sulfonamides
Topical Sulfonamides
General Properties
Antimicrobial Activity
Mode of Action
Bacterial Resistance
Antimicrobial Spectra
Pharmacokinetic Features
Absorption
Distribution
Biotransformation
Excretion
Pharmacokinetic Values
Therapeutic Indications and Dose Rates
Special Clinical Concerns
Adverse Effects and Toxicity
Interactions
Effects on Laboratory Tests
Regulatory Considerations and Drug Withdrawal and Milk Discard Times
Tetracyclines Use in Animals
Classes
General Properties
Antimicrobial Activity
Mode of Action
Bacterial Resistance
Antimicrobial Spectra
Pharmacokinetic Features
Absorption
Distribution
Biotransformation
Excretion
Pharmacokinetic Values
Therapeutic Indications and Dose Rates
Special Clinical Concerns
Adverse Effects and Toxicity
Interactions
Effects on Laboratory Tests
Drug Withdrawal and Milk Discard Times
Phenicols Use in Animals
General Properties
Antimicrobial Activity
Mode of Action
Bacterial Resistance
Antimicrobial Spectra
Pharmacokinetic Features
Absorption
Distribution
Biotransformation
Excretion
Pharmacokinetic Values
Therapeutic Indications and Dose Rates
Special Clinical Concerns
Adverse Effects and Toxicity
Interactions
Effects on Laboratory Tests
Drug Withdrawal and Milk Discard Times
Macrolide Use in Animals
Classes
General Properties
Antimicrobial Activity
Mode of Action
Bacterial Resistance
Antimicrobial Spectra
Pharmacokinetic Features
Absorption
Distribution
Biotransformation
Excretion
Pharmacokinetic Values
Therapeutic Indications and Dose Rates
Special Clinical Concerns
Adverse Effects and Toxicity
Interactions
Effects on Laboratory Tests
Drug Withdrawal and Milk Discard Times
Streptogramins Use in Animals
Lincosamides Use in Animals
General Properties
Antimicrobial Activity
Mode of Action
Bacterial Resistance
Antimicrobial Spectra
Pharmacokinetic Features
Absorption
Distribution
Biotransformation
Excretion
Pharmacokinetic Values
Therapeutic Indications and Dose Rates
Special Clinical Concerns
Adverse Effects and Toxicity
Interactions
Effects on Laboratory Tests
Drug Withdrawal Times
Polymyxins Use in Animals
Bacitracins Use in Animals
Glycopeptides Use in Animals
Novobiocin Sodium Use in Animals
Tiamulin Fumarate Use in Animals
Ionophores Use in Animals
Rifamycins Use in Animals
Nitrofurans Use in Animals
Nitrofurantoin
Nitrofurazone
Furazolidone
Nitroimidazoles Use in Animals
Metronidazole