Dosages of Aminoglycosides
Aminoglycoside | Species | Dosage, Route, and Frequency | Notes |
|---|---|---|---|
Gentamicin | Dogs | 10–14 mg/kg, IM, IV, or SC, q 24 h | Dosage reduction is required in dogs with renal impairment |
Cats | 5–8 mg/kg, IV, IM, or SC, q 24 h | Dosage reduction is required in cats with renal impairment | |
Horses Foals | 7.7-9.7 mg/kg, IV, q 24 h; IM injection causes muscle irritation < 2 weeks of age: 12 mg/kg, IV, q 36 h >2 weeks of age: 6.6 mg/kg, IV, q 24 h | Neonatal foals (< 2 weeks of age, may require higher daily dosing and longer dosing intervals) | |
Swine | 1.1–2.2 mg/kg, PO as medicated water, q 24 h for 3 days | ||
Turkeys | For 1-3 day old poults: 1 mg/poult, SC, in the back of the neck | ||
Streptomycin | Broiler chickens | 22–33 mg/kg, PO as medicated water, q 24 h for up to 5 days | Not for use in layers |
Calves | 22–33 mg/kg, PO as medicated water, q 24 h for up to 5 days | ||
Swine | 22-33 mg/kg as oral medicated water for up to 4 days | ||
Dihydrostreptomycin | Cattle | 11 mg/kg, IM, q 12 h | Not for use in lactating dairy cattle |
Dogs | 11 mg/kg, IM (deep injection), q 12 h for 3 to 5 days or until the urine is free of Leptospira for at least 72 hours as determined by dark-field microscopic examination | ||
Horses | 11 mg/kg, IM (deep injection), q 12 h for 3 to 5 days or until the urine is free of Leptospira for at least 72 hours as determined by dark-field microscopic examination | ||
Swine | 11 mg/kg, IM, q 12 h | ||
Amikacin | Cats | 10–15 mg/kg, IM, IV, or SC, q 24 h | |
Dogs | 15–30 mg/kg, IM, IV, or SC, q 24 h | ||
Horses | 10–mg/kg, IV, q 24 h | ||
Foals | 20–25 mg/kg, IV, q 24 h |