Dosages of Quinolones

Quinolonea

Species

Dosage, Route, and Frequency

Notes

Enrofloxacin

Dogs

5–20 mg/kg, PO, IV, or SC, q 12–24 h

Cats

2.5 mg/kg, PO, IV, or SC, q 12 h; or 5 mg/kg, PO, IV, or SC, q 24 h

Cattle (excluding veal and lactating dairy)

7.5–12.5 mg/kg, SC, once

2.5–5 mg/kg, SC, q 24 h for 3–5 days

ELDU prohibited

Horses

5–10 mg/kg, IV, q 24 h; 5–10 mg/kg, PO, q 24 h

ELDU

Pigs

7.5 mg/kg, IM or SC (postauricular), once

ELDU prohibited

Ciprofloxacin

Dogs, cats

5–15 mg/kg, PO, q 12 h

Off-label, not well absorbed in cats

Marbofloxacin

Cats, dogs

2.75–5.5 mg/kg, PO, q 24 h

Difloxacin

Dogs

5–10 mg/kg, PO, q 24 h

Orbifloxacin

Cats, dogs

2.5–7.5 mg/kg, PO, q 24 h

Pradofloxacin

Cats

7.5 mg/kg, PO, q 24 h

Extralabel use of fluorinated quinolones in food-producing animals is prohibited in the US.

ELDU, extralabel drug use